1 Proteins
DB identifier | UniProt Accession | Secondary Identifier | Organism Name | Length |
---|---|---|---|---|
Ibeam.2229s0006.1.p | PAC:39781857 | Iberis amara | 202 |
Type: | Domain | Name: | Nuclear-interacting partner of ALK/Rsm1-like |
Description: | This entry contains Nuclear-interacting partner of ALK (NIPA) and NIPA like proteins, as well as mRNA export factor Rsm1, all of which contain a C3HC-type zinc finger. The domain represented in this entry is found C-terminal to the zinc-finger like domain . Rsm1 is involved in mRNA export from the nucleus []. NIPA is an essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry []. | Short Name: | NIPA/Rsm1 |
DB identifier | UniProt Accession | Secondary Identifier | Organism Name | Length |
---|---|---|---|---|
Ibeam.2229s0006.1.p | PAC:39781857 | Iberis amara | 202 |