4 GO Annotations
| GO Term | Gene Name |
|---|---|
| GO:0005516 | IPR004178 |
| GO:0015269 | IPR004178 |
| GO:0006813 | IPR004178 |
| GO:0016021 | IPR004178 |
4 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0005516 | IPR004178 |
| GO:0015269 | IPR004178 |
| GO:0006813 | IPR004178 |
| GO:0016021 | IPR004178 |
| Type: | Domain | Name: | Calmodulin-binding domain |
| Description: | Small-conductance Ca2+-activated K+ channels (SK channels) are independent of voltage and gated solely by intracellular Ca2+. These membrane channels are heteromeric complexes that comprise pore-forming alpha-subunits and the Ca2+-binding protein calmodulin (CaM) []. CaM binds to the SK channel through this the CaM-binding domain (CaMBD), which is located in an intracellular region of the alpha-subunit immediately carboxy-terminal to the pore. Channel opening is triggered when Ca2+ binds the EF hands in the N-lobe ofCaM. The structure of this domain complexed with CaM is known []. This domain forms an elongated dimer with a CaM molecule bound at each end; each CaM wraps around three alpha-helices, two from one CaMBD subunit and one from the other. | Short Name: | CaM-bd_dom |
| GO Term | Gene Name |
|---|---|
| GO:0005516 | IPR004178 |
| GO:0015269 | IPR004178 |
| GO:0006813 | IPR004178 |
| GO:0016021 | IPR004178 |
| GO Term | Gene Name |
|---|---|
| GO:0005516 | IPR004178 |
| GO:0015269 | IPR004178 |
| GO:0006813 | IPR004178 |
| GO:0016021 | IPR004178 |
