Protein Domain : IPR011166

Type:  Family Name:  Beta-eliminating lyase family
Description:  Tryptophanase (tryptophan indole-lyase, TNase) () and tyrosine phenol-lyase (TPL) () are related pyridoxal-phosphate dependent homotetrameric enzymes that catalyse the reversible hydrolytic cleavage of L-tryptophan or L-tyrosine to indole or phenol, respectively, and ammonium pyruvate. These two enzymes are very similar in sequence and structure, but show strict substrate specificity. Both TNase and TPL may react by a rare S(E)2-type mechanism []. Collectively, these enzymes are known as the beta-eliminating lyase family. Short Name:  Beta-eliminating_lyase
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2 Child Features

DB identifier Type Name
IPR013440 Family Tryptophanase
IPR013441 Family Tyrosine phenol-lyase

2 Contains

DB identifier Type Name
IPR015421 Domain Pyridoxal phosphate-dependent transferase, major region, subdomain 1
IPR018176 Conserved_site Tryptophanase, conserved site

1 Cross References

Identifier
PIRSF001386

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0016830 IPR011166
GO:0009072 IPR011166

2 Ontology Annotations

GO Term Gene Name
GO:0016830 IPR011166
GO:0009072 IPR011166

0 Parent Features

1 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Bobra.0262s0001.1.p PAC:40707021 Botryococcus braunii 512  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12686128