Protein Domain : IPR029887

Type:  Family Name:  ORM protein, fungi
Description:  This entry represents ORM proteins from fungi, such as Orm1 and Orm2 from budding yeasts and protein C119.09c from fission yeasts. They belong to the ORMDL family, whose members may be involved in protein folding in the ER []. Orm1 and Orm2 mediate sphingolipid homeostasis []. Orm proteins associate with serine palmitoyltransferase (SPT) and negatively regulate SPT activity in response to changes in cellular ceramide levels [, ]. The yeast Orm proteins are regulated by phosphorylation [, ]. Short Name:  ORM_fungi
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0 Child Features

0 Contains

1 Cross References

Identifier
PTHR12665:SF7

0 Found In

5 GO Annotations

GO Term Gene Name
GO:0006986 IPR029887
GO:0090155 IPR029887
GO:0090156 IPR029887
GO:0005789 IPR029887
GO:0035339 IPR029887

5 Ontology Annotations

GO Term Gene Name
GO:0006986 IPR029887
GO:0090155 IPR029887
GO:0090156 IPR029887
GO:0005789 IPR029887
GO:0035339 IPR029887

1 Parent Features

DB identifier Type Name
IPR007203 Family ORMDL family

1 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Cocit.L5324.1.p PAC:41063214 Corymbia citriodora 165  

6 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12093374
            20182505
            20212121
            22328531
            22535525
            22080611