| Type: | Domain | Name: | Transposase, Tn5-like, C-terminal |
| Description: | This domain is found at the C-terminal of Tn5-type transposase proteins. Prokaryotic Tn5 transposase makes two types of DNA contacts (cis-contacts for DNA recognition and trans-contacts for catalysis) as well as protein-protein contacts []. Tn5 transposase employs two cations at its active site during catalysis, which cause conformational changes in the bound DNA and which are required for transposition []. Tn5 transposase has a RnaseH-type alpha/beta/alpha fold. The C-terminal domain forms an orthogonal alpha-bundle structure. | Short Name: | Transposase_Tn5-like_C |
