1 Proteins
DB identifier | UniProt Accession | Secondary Identifier | Organism Name | Length |
---|---|---|---|---|
28069.m000038 | B9TCE9 | PAC:16799857 | Ricinus communis | 162 |
Type: | Family | Name: | Coenzyme A biosynthesis protein |
Description: | Temperature-sensitive mutants of Escherichia coli, defective in the transfer of 3-deoxy-D-manno-octulosonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A, have been used to map KDO transferase activity on the E. coli chromosome []. The KDO transferase gene, designated kdtA, was shown to code for a 43kDa polypeptide. Overexpression of this single gene product greatly stimulates incorporation of two stereochemically distinct KDO residues during lipopolysaccharide biosynthesis in extracts of E. coli [].From these experiments this protein was thought to play a role in lipopolysaccharide biosynthesis, however now it is annotated as phosphopantetheine adenylyltransferase (), which catalyses the reversible transfer of an adenylyl group from ATP to 4'-phosphopantetheine to give dephospho-CoA (DPCOA) and pyrophosphate in the fourth (and penultimate) step of coenzyme A biosynthesis []. | Short Name: | LPS_biosynth |
DB identifier | UniProt Accession | Secondary Identifier | Organism Name | Length |
---|---|---|---|---|
28069.m000038 | B9TCE9 | PAC:16799857 | Ricinus communis | 162 |