Protein Domain : IPR005490

Type:  Domain Name:  L,D-transpeptidase catalytic domain
Description:  This family of proteins are found in a range of bacteria. The conserved region contains a conserved histidine and cysteine, suggesting that these proteins have an enzymatic activity. Several members of this family contain peptidoglycan binding domains. So these proteins may use peptidoglycan or a precursor as a substrate. The molecular structure of YkuD protein shows this domain has a novel tertiary fold consisting of a beta-sandwich with two mixed sheets, one containing five strands and the other, six strands. The two beta-sheets form a cradle capped by an alpha-helix. This domain contains a putative catalytic site with a tetrad of invariant His123, Gly124, Cys139, and Arg141. The stereochemistry of this active site shows similarities to peptidotransferases and sortases, and suggests that the enzymes of this family may play an important role in cell wall biology. This family was formerly called the ErfK/YbiS/YcfS/YnhG family, but is now named after the first protein of known structure. Short Name:  LD_TPept_cat_dom
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0 Child Features

0 Contains

1 Cross References

Identifier
PF03734

1 Found In

DB identifier Type Name
IPR016915 Family Uncharacterised conserved protein UCP029342

1 GO Annotation

GO Term Gene Name
GO:0016740 IPR005490

1 Ontology Annotations

GO Term Gene Name
GO:0016740 IPR005490

0 Parent Features

9 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
41759.m000015 B9TQ31 PAC:16827439 Ricinus communis 249  
57260.m000018 B9TPQ9 PAC:16829030 Ricinus communis 119  
28761.m000036 B9TCA8 PAC:16801676 Ricinus communis 197  
Brdisv1pangenome1006860m.p PAC:33619762 Brachypodium distachyon Pangenome 313  
Brdisv1pangenome1010171m.p PAC:33607854 Brachypodium distachyon Pangenome 558  
Brdisv1pangenome1010387m.p PAC:33624733 Brachypodium distachyon Pangenome 337  
Brdisv1BdTR11A1048357m.p PAC:35696048 Brachypodium distachyon BdTR11a 299  
Brdisv1BdTR11A1048024m.p PAC:35690588 Brachypodium distachyon BdTR11a 558  
Brdisv1BdTR11A1041649m.p PAC:35696804 Brachypodium distachyon BdTR11a 313  

0 Publications