Protein Domain : IPR001702

Type:  Family Name:  Porin, Gram-negative type
Description:  Porins are found in the outer membranes of Gram-negative bacteria, mitochondria and chloroplasts, where they form ion-selective channels forsmall hydrophilic molecules (up to ~600 D) [, ]. X-ray structureanalyses of several bacterial porins [, , ] have revealed a large 16-strandedanti-parallel beta-barrel structure enclosing the transmembrane pore, by contrast with all other integral membrane proteins described to date,which are alpha-helical. Three subunits form a trimer; the 3-fold axis is approximately parallel to the barrel axes and is assumed to beperpendicular to the membrane plane.From the range of porins now known, similarities have been observed between porins from different species, and between porins of different specificitywithin the same species. But most porins cannot be related to each other on the basis of sequence alone, and this is reflected in the lengths of theknown porin sequences, which range from 282-483 residues/monomer.This entry represents porins from Gram-negative bacteria. Short Name:  Porin_Gram-ve

2 Child Features

DB identifier Type Name
IPR002299 Family Porin, Neisseria sp. type
IPR001897 Family Porin, gammaproteobacterial

1 Contains

DB identifier Type Name
IPR013793 Conserved_site Porin, Gram-negative type, conserved site

2 Cross Referencess

Identifier
PF00267
PR00182

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0015288 IPR001702
GO:0006810 IPR001702
GO:0016020 IPR001702

3 Ontology Annotations

GO Term Gene Name
GO:0015288 IPR001702
GO:0006810 IPR001702
GO:0016020 IPR001702

0 Parent Features

4 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
53432.m000013 B9TNP8 PAC:16828615 Ricinus communis 286  
28815.m000075 B9T9V6 PAC:16801730 Ricinus communis 387  
Araha.11756s0079.1.p PAC:28856434 Arabidopsis halleri 380  
Solyc00g030105.1.1 PAC:41467041 Solanum lycopersicum 265  

5 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1707373
            7525973
            1725488
            1373213
            2178269