Protein Domain : IPR003138

Type:  Family Name:  Picornavirus coat protein VP4
Description:  Picornaviruses are single-stranded RNA viruses. Processing of the viral polyprotein by picornains 3C and 2A generates capsid proteins VP0, VP1 and VP3, but VP0 undergoes an autolytic cleavage during virion assembly to generate capsid proteins VP2 and VP4 []. The autolytic cleavage was originally thought to be the action of a serine-type peptidase, but from analogy with the similar autoproteolytic cleavages that are known for capsid proteins from nodaviruses (MEROPS peptidase family N1), tetraviruses (MEROPS peptidase family N2), picobirnaviruses (MEROPS peptidase family N5) and reoviruses (MEROPS peptidase family N7), it is more likely that VP0 is an asparagine-type peptidase; autocatalytic cleavage being promoted by cyclization of a conserved asparagine. . Short Name:  Pico_P1A
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0 Child Features

0 Contains

2 Cross Referencess

Identifier
PF02226
G3DSA:4.10.80.10

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0005198 IPR003138
GO:0019028 IPR003138

2 Ontology Annotations

GO Term Gene Name
GO:0005198 IPR003138
GO:0019028 IPR003138

0 Parent Features

160 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
29733.m000753 B9S854 PAC:16807087 Ricinus communis 58  
orange1.1g041999m A0A067D4N7 PAC:18096093 Citrus sinensis 151  
AT3G13845.1 Q8GW60 PAC:19658753 Arabidopsis thaliana 70  
Potri.010G124200.1 PAC:26982857 Populus trichocarpa 285  
46627 I0Z3G9 PAC:27389989 Coccomyxa subellipsoidea C-169 360  
Migut.D01494.1.p A0A022RCS5 PAC:28928821 Mimulus guttatus 594  
Migut.H02318.1.p PAC:28952338 Mimulus guttatus 233  
Migut.N00666.1.p A0A022RJP3 PAC:28923160 Mimulus guttatus 424  
Araha.2716s0004.1.p PAC:28838492 Arabidopsis halleri 777  
Araha.4235s0017.1.p PAC:28839352 Arabidopsis halleri 70  
Cagra.1884s0001.1.p PAC:28909481 Capsella grandiflora 108  
Cagra.0736s0020.2.p PAC:28899808 Capsella grandiflora 70  
Cagra.0736s0020.1.p PAC:28899809 Capsella grandiflora 70  
Glyma.05G178600.1.p K7KQY3 PAC:30526343 Glycine max 111  
Bostr.28625s0324.1.p PAC:30679289 Boechera stricta 69  
Medtr7g006475.1 A0A072TVL1 PAC:31082947 Medicago truncatula 110  
Medtr8g009265.1 PAC:31069521 Medicago truncatula 89  
SapurV1A.4404s0010.1.p PAC:31426511 Salix purpurea 182  
Traes_3B_E0AF8BE97.1 PAC:31923170 Triticum aestivum 197  
Sphfalx0063s0029.1.p PAC:32612335 Sphagnum fallax 707  
Sevir.4G212900.1.p A0A4U6V2Z3 PAC:32647612 Setaria viridis 372  
Seita.4G204200.1.p K3Y2G6 PAC:32707037 Setaria italica 372  
Bradi4g24333.1.p A0A2K2CPY4 PAC:32790819 Brachypodium distachyon 120  
Bradi4g24333.2.p A0A2K2CPY4 PAC:32790820 Brachypodium distachyon 120  
Brdisv1Uni21025727m.p PAC:33253996 Brachypodium distachyon Uni2 120  
Brdisv1Bd3-1_r1028053m.p PAC:33324039 Brachypodium distachyon Bd3-1 120  
Brdisv1BdTR7a1027074m.p A0A2K2CPY4 PAC:33335403 Brachypodium distachyon BdTR7a 120  
Brdisv20Bd21Ref1039725m.p A0A2K2CPY4 PAC:33452292 Brachypodium distachyon Bd21 AnntCtrl 120  
Brdisv1Tek-41014080m.p PAC:33476121 Brachypodium distachyon Tek-4 96  
Brdisv1pangenome1052939m.p A0A2K2CPY4 PAC:33606902 Brachypodium distachyon Pangenome 120  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            6283126