3 Ontology Annotations
GO Term | Gene Name |
---|---|
GO:0003684 | IPR002706 |
GO:0000012 | IPR002706 |
GO:0005634 | IPR002706 |
Type: | Domain | Name: | DNA-repair protein Xrcc1, N-terminal |
Description: | DNA-repair protein Xrcc1 functions in the repair of single-strand DNA breaks in mammalian cells and forms a repair complex with beta-Pol, ligase III and PARP []. The NMR solution structure of the Xrcc1 N-terminal domain (Xrcc1 NTD) shows that the structural core is a beta-sandwich with beta-strands connected by loops, three helices and two short two-stranded beta-sheets at each connection side. The Xrcc1 NTD specifically binds single-strand break DNA (gapped and nicked) and a gapped DNA-beta-Pol complex []. | Short Name: | Xrcc1_N |
GO Term | Gene Name |
---|---|
GO:0003684 | IPR002706 |
GO:0000012 | IPR002706 |
GO:0005634 | IPR002706 |