Protein Domain : IPR026153

Type:  Family Name:  Treslin
Description:  Treslin, a TopBP1-interacting protein, is necessary for DNA replication in vertebrates []. Prior to the initiation of DNA replication, treslin associates with TopBP1 in a Cdk2-dependent manner []. The proteins then collaborate in the Cdk2-mediated loading of Cdc45 onto replication origins [].Treslin is also an important checkpoint regulator, and is required to prevent mitotic entry after treatment with ionizing radiation []. Short Name:  Treslin
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0 Child Features

0 Contains

1 Cross References

Identifier
PTHR21556

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0006260 IPR026153
GO:0010212 IPR026153
GO:0033314 IPR026153
GO:0005634 IPR026153

4 Ontology Annotations

GO Term Gene Name
GO:0006260 IPR026153
GO:0010212 IPR026153
GO:0033314 IPR026153
GO:0005634 IPR026153

0 Parent Features

336 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
30169.m006553 B9RIN9 PAC:16821353 Ricinus communis 981  
Cucsa.095640.1 A0A0A0KVT3 PAC:16957919 Cucumis sativus 1012  
Cucsa.095640.2 A0A0A0KVT3 PAC:16957920 Cucumis sativus 1012  
AT5G52950.1 F4KHP4 PAC:19672020 Arabidopsis thaliana 948  
Thhalv10012590m V4KZ04 PAC:20206237 Eutrema salsugineum 951  
Lus10039318 PAC:23175665 Linum usitatissimum 589  
Lus10027565 PAC:23144481 Linum usitatissimum 1006  
Potri.012G033800.1 A0A2K1Y874 PAC:27049691 Populus trichocarpa 997  
Gorai.006G200000.1 A0A0D2S6K7 PAC:26831779 Gossypium raimondii 972  
Thecc1EG015315t3 A0A061G1E7 PAC:27447086 Theobroma cacao 834  
Thecc1EG015315t2 A0A061G0N2 PAC:27447088 Theobroma cacao 673  
Thecc1EG015315t1 A0A061G8M8 PAC:27447085 Theobroma cacao 1014  
Migut.F00255.1.p A0A022QB33 PAC:28933888 Mimulus guttatus 931  
Cagra.0084s0040.1.p PAC:28895382 Capsella grandiflora 949  
Glyma.16G069100.3.p A0A0R0FMC1 PAC:30559342 Glycine max 872  
Glyma.16G069100.1.p I1MLS9 PAC:30559340 Glycine max 987  
Glyma.16G069100.2.p K7MFL4 PAC:30559341 Glycine max 966  
Brara.B01488.1.p A0A398A972 PAC:30606892 Brassica rapa FPsc 942  
Brara.J00805.1.p A0A397XR94 PAC:30613947 Brassica rapa FPsc 841  
Bostr.7305s0082.1.p PAC:30678071 Boechera stricta 947  
Medtr8g058270.1 G7LBX4 PAC:31071021 Medicago truncatula 980  
SapurV1A.0202s0040.1.p PAC:31442183 Salix purpurea 994  
evm_27.model.AmTr_v1.0_scaffold00075.11 W1PC08 PAC:31556939 Amborella trichopoda 950  
Traes_3AS_014077463.1 PAC:31882398 Triticum aestivum 571  
Traes_3B_05BA47D87.1 PAC:31905852 Triticum aestivum 781  
Traes_3DS_CB3877770.1 PAC:31761121 Triticum aestivum 283  
Eucgr.K00315.1.p A0A058ZYH7 PAC:32068087 Eucalyptus grandis 1001  
Prupe.2G305400.1.p A0A251QNZ9 PAC:32079389 Prunus persica 1009  
GSMUA_Achr6P14210_001 PAC:32318204 Musa acuminata 885  
Manes.06G155900.1.p A0A2C9VSP9 PAC:32348002 Manihot esculenta 1001  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            20116089
            21646402
            20080954