Type: | Domain | Name: | Cathepsin C exclusion |
Description: | Cathepsin C (dipeptidyl peptidase I) is the physiological activator of a group of serine proteases. This protein corresponds to the exclusion domain whose structure excludes the approach of a polypeptide apart from its termini. It forms an enclosed beta barrel structure composed from 8 anti-parallel beta strands []. Based on a structural comparison and interaction data, it is suggested that the exclusion domain originates from a metallo-protease inhibitor []. | Short Name: | CathepsinC_exc |