Protein Domain : IPR006533

Type:  Family Name:  Type VI secretion system, RhsGE-associated Vgr protein
Description:  Type VI secretion system (T6SS) appears to be confined to Proteobacteria. It is important for bacterial pathogenesis, but it is also found in non-pathogenic bacteria, suggesting that T6SS involvement is not limited to virulence []. T6SS was identified in Vibrio cholerae [] and Pseudomonas aeruginosa [], and exports Hcp (Haemolysin-Coregulated Protein) and a class of proteins named Vgr (Val-Gly Repeats), whose exact function is still speculative. In addition to Vgr and Hcp proteins, T6SS is characterised by the presence of an AAA+ Clp-like ATPase and of two additional genes icmF and dotU, encoding homologues of T4SS stabilising proteins []. This entry represent the Vgr family of proteins, associated with some classes of Rhs elements (Rhs classes G and E). Rsh (rearrangement hot-spot) elements are repetitious sequences identified in certain Escherichia coli strains [, ]. Short Name:  T6SS_Vgr_RhsGE
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1 Child Features

DB identifier Type Name
IPR017847 Family Type VI secretion system, RhsGE-associated Vgr family subset

1 Contains

DB identifier Type Name
IPR006531 Domain Gp5 N-terminal

1 Cross References

Identifier
TIGR01646

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

7 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
30644.m000017 B9THQ7 PAC:16824523 Ricinus communis 354  
33391.m000016 B9TF24 PAC:16825816 Ricinus communis 495  
50821.m000013 B9TM02 PAC:16828311 Ricinus communis 264  
57265.m000016 B9TMD1 PAC:16829031 Ricinus communis 310  
Medtr0397s0010.1 A0A072TEL1 PAC:31106192 Medicago truncatula 4070  
Medtr0980s0010.1 A0A072TEM5 PAC:31076884 Medicago truncatula 1198  
Brdisv1pangenome1009489m.p PAC:33657628 Brachypodium distachyon Pangenome 892  

6 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9696756
            16763151
            16432199
            15385502
            19284603
            10673005