Protein Domain : IPR013752

Type:  Domain Name:  Ketopantoate reductase, C-terminal domain
Description:  This is the C-terminal domain of 2-dehydropantoate 2-reductases also known as ketopantoate reductases []. The reaction catalysed by this enzyme is: (R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH. It is required for the synthesis of thiamine via the the alternative pyrimidine biosynthetic (APB) pathway [, ]. Short Name:  KPA_reductase
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0 Child Features

0 Contains

1 Cross References

Identifier
PF08546

1 Found In

DB identifier Type Name
IPR003710 Family Ketopantoate reductase ApbA/PanE

3 GO Annotations

GO Term Gene Name
GO:0016491 IPR013752
GO:0050661 IPR013752
GO:0055114 IPR013752

3 Ontology Annotations

GO Term Gene Name
GO:0016491 IPR013752
GO:0050661 IPR013752
GO:0055114 IPR013752

1 Parent Features

DB identifier Type Name
IPR013328 Domain 6-phosphogluconate dehydrogenase, domain 2

12 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
31903.m000020 B9TFA4 PAC:16825230 Ricinus communis 195  
64024 C1EGX0 PAC:27403801 Micromonas sp RCC299 401  
59513 C1E8W3 PAC:27402134 Micromonas sp RCC299 448  
13695 A4RQW9 PAC:27417895 Ostreococcus lucimarinus 187  
Cre03.g163350.t1.2 A0A2K3DWJ9 PAC:30787294 Chlamydomonas reinhardtii 689  
Dusal.0003s00019.1.p PAC:33187491 Dunaliella salina 262  
Brdisv1pangenome1008681m.p PAC:33657092 Brachypodium distachyon Pangenome 585  
Brdisv1BdTR11A1044715m.p PAC:35690919 Brachypodium distachyon BdTR11a 585  
Cz07g25220.t1 PAC:38245998 Chromochloris zofingiensis 376  
Cocit.L4763.1.p PAC:41063287 Corymbia citriodora 354  
Vocar.0005s0187.1.p PAC:32883517 Volvox carteri 461  
Vocar.0005s0187.2.p PAC:32883518 Volvox carteri 460  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9488683
            9721324
            11724562