Protein Domain : IPR002371

Type:  Family Name:  Flagellar hook-associated protein, FlgK
Description:  Within the bacterial flagellum, the basal-body rod, the hook, the hook- associated proteins (HAPs), and the helical filament together constitute an axial substructure whose elements share structural features and a common export pathway []. The amino acid sequences of the hook protein and of the three hook-associated proteins of Salmonella typhimuriumhave been deduced from the DNA sequences of their structural genes (flgE, flgK, flgL and fliD respectively).These sequences have been compared with each other and with those for the filament protein (flagellin) and four rod proteins. The hook proteinwas found to be most similar to the distal rod protein (FlgG) and the proximal hook-associated protein (HAP1), which are thought to be attached to the proximal anddistal ends of the hook, the similarities being most pronounced near the N- and C-termini.It is thought that the axial proteins may adopt amphipathic alpha-helical conformations at their N- and C-termini. These regions of the filament andhook are believed to be responsible for quaternary interactions between subunits. Interaction between N- and C-terminal alpha-helices may beimportant in the formation of the axial structures of the flagellum. Although consensus sequences have been noted, no consensus extends to theentire set of axial proteins. Thus the basis for recognition of a protein for export by the flagellum-specific pathway remains to be identified. Short Name:  Flagellar_hook-assoc_FlgK
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0 Child Features

2 Contains

DB identifier Type Name
IPR001444 Domain Flagellar basal body rod protein, N-terminal
IPR010930 Domain Flagellar basal-body/hook protein, C-terminal domain

2 Cross Referencess

Identifier
PR01005
TIGR02492

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0005198 IPR002371
GO:0044780 IPR002371
GO:0009424 IPR002371

3 Ontology Annotations

GO Term Gene Name
GO:0005198 IPR002371
GO:0044780 IPR002371
GO:0009424 IPR002371

0 Parent Features

4 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
32479.m000018 B9TEN6 PAC:16825442 Ricinus communis 439  
33765.m000026 PAC:16825979 Ricinus communis 273  
49101.m000018 B9TJH0 PAC:16828146 Ricinus communis 283  
Araha.11756s0069.1.p PAC:28856240 Arabidopsis halleri 533  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            2193164