Protein Domain : IPR002196

Type:  Family Name:  Glycoside hydrolase, family 24
Description:  O-Glycosyl hydrolases () are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [, ]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site.Glycoside hydrolase family 24 comprises enzymes with only one known activity; lysozyme ().This entry includes Bacteriophage lambdalysozyme and Escherichia coliendolysin []. Lysozyme helps to release mature phage particles from the cell wall by breaking down the peptidoglycan. The enzyme hydrolyses the 1,4-beta linkages between N-acetyl-D-glucosamine and N-acetylmuramic acid in peptidoglycan heteropolymers of prokaryotic cell walls. E. coli endolysin also functions in bacterial cell lysis and acts as a transglycosylase. The Bacteriophage T4lysozyme structure contains 2 domains, the interface between which forms the active-site cleft. The N terminus of the 2 domains undergoes a 'hinge-bending' motion about an axis passing through the molecular waist [, ]. This mobility is thought to be important in allowing access of substrates to the enzyme active site. Short Name:  Glyco_hydro_24
Paste the following link

1 Child Features

DB identifier Type Name
IPR001165 Family T4-type lysozyme

0 Contains

1 Cross References

Identifier
PF00959

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0003796 IPR002196
GO:0009253 IPR002196
GO:0016998 IPR002196

3 Ontology Annotations

GO Term Gene Name
GO:0003796 IPR002196
GO:0009253 IPR002196
GO:0016998 IPR002196

0 Parent Features

10 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
32526.m000035 B9TDP0 PAC:16825463 Ricinus communis 148  
12587 I0Z6C2 PAC:27390839 Coccomyxa subellipsoidea C-169 143  
Medtr0701s0010.1 A0A072TF36 PAC:31092273 Medicago truncatula 409  
Brdisv1pangenome1005593m.p PAC:33658875 Brachypodium distachyon Pangenome 129  
Brdisv1pangenome1006122m.p PAC:33621410 Brachypodium distachyon Pangenome 145  
Brdisv1BdTR11A1029436m.p PAC:35675777 Brachypodium distachyon BdTR11a 129  
Brdisv1BdTR11A1037308m.p PAC:35684601 Brachypodium distachyon BdTR11a 145  
Misin11G257000.1.p PAC:40482269 Miscanthus sinensis 286  
Misin11G257000.2.p PAC:40482270 Miscanthus sinensis 283  
Misin11G257000.3.p PAC:40482271 Miscanthus sinensis 252  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            7624375
            8535779
            2234094
            3586019