Protein Domain : IPR002112

Type:  Family Name:  Transcription factor Jun
Description:  The transcription factor activator protein (AP)-1 consists of Jun (c-Jun, JunB, and JunD), Fos (c-Fos, FosB, Fra1, and Fra2), ATF (ATFa, ATF-2 and ATF-3) and JDP (JDP-1 and JDP-2) family members []. They are basic leucine zipper transcription factors that play a central role in regulating gene transcription in various biological processes []. This entry includes Jun family members. AP-1 proteins have a alpha-helical bZIP domain, which contains a basic DNA-binding region and regularly spaced leucine residues known as the leucine zipper motif []. They have similar protein structure and can either form homodimers or form heterodimers with other AP-1 proteins (predominantly with Jun proteins), which can then bind to TRE-like sequences (consensus sequence 5'-TGAG/CTCA-3') []. Each of these proteins are expressed in different tissues and can be regulated in different ways, which means that every cell type has a complex mixture of AP-1 dimers with subtly different functions []. Short Name:  Leuzip_Jun
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3 Child Features

DB identifier Type Name
IPR015558 Family Transcription Factor c-Jun/v-Jun
IPR029822 Family Transcription factor JunB
IPR029823 Family Transcription factor JunD

1 Contains

DB identifier Type Name
IPR008917 Domain Transcription factor, Skn-1-like, DNA-binding domain

1 Cross References

Identifier
PR00043

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0003677 IPR002112
GO:0003700 IPR002112
GO:0006355 IPR002112

3 Ontology Annotations

GO Term Gene Name
GO:0003677 IPR002112
GO:0003700 IPR002112
GO:0006355 IPR002112

0 Parent Features

7 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
55072.m000012 B9THV1 PAC:16828774 Ricinus communis 101  
orange1.1g045005m A0A067ESJ3 PAC:18111152 Citrus sinensis 149  
Sobic.001G075900.1.p C5WZ82 PAC:37941665 Sorghum bicolor 199  
Gohir.A05G081000.2.p PAC:38121890 Gossypium hirsutum 83  
SbRio.01G078900.1.p C5WZ82 PAC:38992557 Sorghum bicolor Rio 199  
SbiRTX430.01G077600.1.p C5WZ82 PAC:43584846 Sorghum bicolor RTx430 199  
SbiBTX642.01G076300.1.p C5WZ82 PAC:44441299 Sorghum bicolor BTx642 199  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12424143
            23787991
            15564374