Protein Domain : IPR012969

Type:  Family Name:  Fibrinogen binding protein
Description:  Proteins in this family bind to fibrinogen. Fibrinogen is capable of binding to a wide number of endogenous proteins and cell receptors during haemostasis, including binding to platelets to promote their aggregation []. Included in this family is receptor FbsA () from the pathogen Streptococcus agalactiae, which is responsible for causing endocarditis in humans. FbsA is considered an important virulence factor that is capable of binding fibrinogen, through which it elicits platelet aggregation and adherence to the extracellular matrix. This enables the bacteria to invade the pulmonary epithelium, which may be a prerequisite for infection [].This entry also contains Eukaryotic translation initiation factor 4 gamma, which is a component of the protein complex eIF4F and is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome []. Short Name:  Fibrinogen_BP
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0 Child Features

0 Contains

1 Cross References

Identifier
PF08017

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

10 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Brara.E00291.1.p A0A397Z648 PAC:30623551 Brassica rapa FPsc 993  
Traes_7AS_1BC3A985D.1 PAC:31796507 Triticum aestivum 977  
Traes_7AS_1BC3A985D.2 PAC:31796508 Triticum aestivum 470  
Dusal.0137s00026.1.p PAC:33195612 Dunaliella salina 652  
Dusal.0137s00026.2.p PAC:33195613 Dunaliella salina 652  
Luann.0021s0355.1.p PAC:39400566 Lunaria annua 134  
Mamar.0079s0206.3.p PAC:39425632 Malcolmia maritima 522  
Mamar.0079s0206.2.p PAC:39425633 Malcolmia maritima 514  
Nycol.E01335.1.p PAC:44532517 Nymphaea colorata 277  
Sialb.1139s0011.1.p PAC:45648872 Sinapis alba 248  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            15837518
            15383464
            12581158