Protein Domain : IPR017997

Type:  Family Name:  Vinculin
Description:  Vinculin is an actin filament (F-actin) binding protein involved in cell-matrix adhesion and cell-cell adhesion []. In addition to actin, vinculin interacts with other structuralproteins such as talin and alpha-actinins.Vinculin is a large protein of 116 kDa (about a 1000 residues). Structurally the protein consists of an acidic N-terminal domain of about 90 kDa separated from a basic C-terminal domain of about 25 kDa by a proline-rich region of about 50 residues. The central part of the N-terminal domain consists of a variable number (3 in vertebrates, 2 in Caenorhabditis elegans) of repeats of a 110 amino acids domain. Short Name:  Vinculin

0 Child Features

0 Contains

1 Cross References

Identifier
PTHR18914:SF22

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0051015 IPR017997
GO:0007155 IPR017997
GO:0007160 IPR017997

3 Ontology Annotations

GO Term Gene Name
GO:0051015 IPR017997
GO:0007155 IPR017997
GO:0007160 IPR017997

1 Parent Features

DB identifier Type Name
IPR006077 Family Vinculin/alpha-catenin

2 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Brara.E02268.1.p A0A397ZE56 PAC:30625074 Brassica rapa FPsc 459  
Prupe.4G102300.1.p A0A251PIF4 PAC:32095619 Prunus persica 273  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            2112986