Protein Domain : IPR022409

Type:  Domain Name:  PKD/Chitinase domain
Description:  The PKD (Polycystic Kidney Disease) domain was first identified in the Polycystic Kidney Disease protein, polycystin-1 (PDK1 gene), and contains an Ig-like fold consisting of a beta-sandwich of seven strands in two sheets with a Greek key topology, although some members have additional strands []. Polycystin-1 is a large cell-surface glycoprotein involved in adhesive protein-protein and protein-carbohydrate interactions; however it is not clear if the PKD domain mediates any of these interactions. PKD domains are also found in other proteins, usually in the extracellular parts of proteins involved in interactions with other proteins. For example, domains with a PKD-type fold are found in archaeal surface layer proteins that protect the cell from extreme environments [], and in the human VPS10 domain-containing receptor SorCS2 []. Short Name:  PKD/Chitinase_dom
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1 Child Features

DB identifier Type Name
IPR000601 Domain PKD domain

0 Contains

1 Cross References

Identifier
SM00089

3 Found Ins

DB identifier Type Name
IPR002859 Domain PKD/REJ-like domain
IPR002169 Family Peptidase M9A/M9B, collagenase, bacterial
IPR013540 Domain Chitinase A N-terminal

0 GO Annotation

0 Ontology Annotations

0 Parent Features

7 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Cre09.g396750.t3.1 A0A2K3DD42 PAC:30781239 Chlamydomonas reinhardtii 1420  
Cre09.g396750.t2.1 A0A2K3DD46 PAC:30781238 Chlamydomonas reinhardtii 1428  
Cre09.g396750.t1.1 A0A2K3DD47 PAC:30781237 Chlamydomonas reinhardtii 1465  
Brdisv1pangenome1005570m.p PAC:33635503 Brachypodium distachyon Pangenome 744  
Brdisv1BdTR11A1029413m.p PAC:35679346 Brachypodium distachyon BdTR11a 744  
Cz05g34140.t1 PAC:38242381 Chromochloris zofingiensis 1721  
Cz12g07230.t1 PAC:38240137 Chromochloris zofingiensis 1899  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9889186
            12377130
            11499680