Protein Domain : IPR003004

Type:  Family Name:  GspF/PilC family
Description:  The general (type II) secretion pathway (Gsp) within Gram-negative bacteria is a signal sequence-dependent process responsible for protein export [, , ]. The process has two stages: exoproteins are first translocated across the inner membrane by the general signal-dependent export pathway (GEP), and then across the outer membrane by a species-specific accessory mechanism.The Gsp is a composite of several proteins, one of which is termed general secretion pathway protein F (GspF), which is thought to be located within the inner membrane []. This suggests that protein F is part of the GEP apparatus, which aids translocation of exoproteins from the cytoplasm to the periplasm, prior to transport across the outer membrane. GspF is a highly hyrdophobic protein containing ~400 amino acids.This entry represents GspD and close homologues, including the type IV pilin assembly protein PilC. Short Name:  GspF/PilC
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1 Child Features

DB identifier Type Name
IPR011850 Family General secretion pathway protein F

2 Contains

DB identifier Type Name
IPR018076 Domain Type II secretion system F domain
IPR001992 Conserved_site Type II secretion system conserved site

1 Cross References

Identifier
PR00812

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

2 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
MgNONTOL.D2364.1.p PAC:43592340 Mimulus guttatus NONTOL 498  
Zosma07g00870 PAC:50101832 Zostera marina 361  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8438237
            1592799
            1365398
            1588814