Protein Domain : IPR000976

Type:  Domain Name:  Wilm's tumour protein, N-terminal
Description:  Wilm's tumour (WT) is an embryonal malignancy of the kidney, affecting around 1 in 10,000 infants. It occurs in both sporadic and hereditary forms. Inactivation of WT1 is one of the causes of Wilm's tumour. Defects in the WT1 gene are also associated with Denys-Drash Syndrome (DDS), which is characterised by typical nephropathy and genital abnormalities. The WT1 gene product shows similarity to the zinc fingers of the mammalian growth regulated EGR1 and EGR2 proteins [, , , ]. Short Name:  Wilms_tumour_N
Paste the following link

0 Child Features

0 Contains

1 Cross References

Identifier
PF02165

1 Found In

DB identifier Type Name
IPR017987 Family Wilm's tumour protein

2 GO Annotations

GO Term Gene Name
GO:0006355 IPR000976
GO:0005634 IPR000976

2 Ontology Annotations

GO Term Gene Name
GO:0006355 IPR000976
GO:0005634 IPR000976

0 Parent Features

1 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Urofu.2G245700.1.p PAC:50153998 Urochloa fusca 259  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8393820
            1671709
            2154702
            1317572