Protein Domain : IPR026577

Type:  Domain Name:  Replication modulator SeqA, C-terminal DNA-binding domain
Description:  The binding of SeqA protein to hemimethylated GATC sequences is important in the negative modulation of chromosomal initiation at oriC, and in the formation of SeqA foci necessary for Escherichia colichromosome segregation []. SeqA tetramers are able to aggregate or multimerize in a reversible, concentration-dependent manner []. Apart from its function in the control of DNA replication, SeqA may also be a specific transcription factor [].The C-terminal domain binds DNA, binding to hemimethylated GATC sequences at oriC [, ]. The structure of the C-terminal domain consists of seven alpha-helices and three-stranded beta-sheet. Short Name:  SeqA_DNA-bd_C
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0 Child Features

0 Contains

2 Cross Referencess

Identifier
G3DSA:1.20.1380.10
SSF82808

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0003677 IPR026577

1 Ontology Annotations

GO Term Gene Name
GO:0003677 IPR026577

0 Parent Features

34 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Cucsa.282840.1 A0A0A0KWK8 PAC:16974440 Cucumis sativus 266  
Glyma.13G188200.1.p A0A0R0GQT8 PAC:30503049 Glycine max 73  
Medtr6g034890.1 G7ZXG3 PAC:31101905 Medicago truncatula 138  
Medtr6g043740.1 G7KJ00 PAC:31103000 Medicago truncatula 270  
Brdisv1S8iiC1033962m.p PAC:33870496 Brachypodium distachyon S8iic 324  
Phvul.009G097700.1.p V7AUT3 PAC:37149165 Phaseolus vulgaris 1149  
Gohir.A05G083200.1.p PAC:38120605 Gossypium hirsutum 178  
AH010469-RA PAC:38170277 Amaranthus hypochondriacus 875  
BdiBd21-3.4G0453400.1.p PAC:38201046 Brachypodium distachyon Bd21-3 495  
Alyli.0088s0111.1.p PAC:39190821 Alyssum linifolium 302  
Desop.0014s0103.1.p PAC:39664717 Descurainia sophioides 118  
Eruve.4276s0002.1.p PAC:39944129 Eruca vesicaria 766  
Crahi.0816s0012.1.p PAC:39984567 Crambe hispanica 241  
Distr.0241s0159.1.p PAC:40012649 Diptychocarpus strictus 480  
Brasy2G487700.1.p PAC:40071768 Brachypodium sylvaticum 104  
Glyma.13G188200.1.p A0A0R0GQT8 PAC:41137919 Glycine max 73  
Gomus.A05G088700.1.p A0A5D2Z4U3 PAC:42097997 Gossypium mustelinum 178  
Gotom.A05G090200.1.p A0A5D2QDB2 PAC:42174050 Gossypium tomentosum 164  
Gotom.D09G089500.1.p A0A5D2JEL3 PAC:42235215 Gossypium tomentosum 820  
Gobar.A05G087400.1.p A0A2P5VZ27 PAC:42278399 Gossypium barbadense 164  
Gobar.D09G082000.1.p A0A5J5Q2D7 PAC:42306963 Gossypium barbadense 820  
Gohir.A05G083200.1.p PAC:42420435 Gossypium hirsutum 178  
Godar.A05G089600.1.p A0A5D2GDZ2 PAC:42512104 Gossypium darwinii 164  
arahy.Tifrunner.gnm1.ann1.DF0SS3.1 PAC:42603520 Arachis hypogaea 395  
PvUI111.09G099600.1.p V7AUT3 PAC:42817110 Phaseolus vulgaris UI111 1149  
BdiBd21-3.4G0453400.1.p PAC:42947451 Brachypodium distachyon Bd21-3 495  
CepurR40.6G059700.1.p PAC:43012762 Ceratodon purpureus R40 83  
CepurGG1.6G055900.1.p PAC:43058307 Ceratodon purpureus GG1 83  
EL10Ac6g13822.1 PAC:43413719 Beta vulgaris 105  
SbiRTX430.02G304800.1.p PAC:43560888 Sorghum bicolor RTx430 70  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11457824
            11442835
            14704346
            12379844