Protein Domain : IPR003417

Type:  Family Name:  Core binding factor, beta subunit
Description:  Core binding factor (CBF) is a heterodimeric transcription factor essential for genetic regulation of hematopoiesis and osteogenesis. The beta subunit binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including Murine leukemia virus, Polyomavirus enhancer, T-cell receptor enhancers etc. The beta subunit enhances DNA-binding ability of the alpha subunit in vitro, and has been show to have a structure related to the OB fold []. Also included in this family are the Drosophila melanogasterbrother and big brother proteins, which regulate the DNA-binding properties of Runt. Short Name:  CBF_beta
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0 Child Features

0 Contains

4 Cross Referencess

Identifier
PTHR10276
PF02312
G3DSA:2.40.250.10
SSF50723

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0003713 IPR003417
GO:0005634 IPR003417

2 Ontology Annotations

GO Term Gene Name
GO:0003713 IPR003417
GO:0005634 IPR003417

0 Parent Features

84 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Cucsa.322390.1 PAC:16977752 Cucumis sativus 129  
orange1.1g034657m A0A067H4K1 PAC:18137051 Citrus sinensis 88  
Ciclev10022291m V4TDR1 PAC:20807400 Citrus clementina 205  
Potri.001G126800.1 A0A2K2BWQ2 PAC:27040525 Populus trichocarpa 500  
Gorai.003G030600.1 A0A0D2QMK9 PAC:26797915 Gossypium raimondii 111  
Gorai.005G220200.1 A0A0D2NGW6 PAC:26806437 Gossypium raimondii 117  
14631 A4RUH8 PAC:27413044 Ostreococcus lucimarinus 107  
Medtr5g021990.1 G7JW73 PAC:31090735 Medicago truncatula 215  
Spipo9G0055600 PAC:31514338 Spirodela polyrhiza 143  
evm_27.model.AmTr_v1.0_scaffold00031.114 U5D2Z9 PAC:31551843 Amborella trichopoda 90  
evm_27.model.AmTr_v1.0_scaffold00066.11 U5DD13 PAC:31564046 Amborella trichopoda 435  
Aco007005.1 PAC:33047833 Ananas comosus 908  
Aco004010.1 PAC:33030566 Ananas comosus 1176  
Aco025504.1 PAC:33041315 Ananas comosus 732  
Aqcoe7G312900.2.p A0A2G5DQP7 PAC:33071344 Aquilegia coerulea 84  
Aqcoe7G312900.1.p A0A2G5DQP7 PAC:33071343 Aquilegia coerulea 84  
Tp57577_TGAC_v2_mRNA4397 PAC:35960594 Trifolium pratense 67  
Phvul.001G005600.1.p V7CTH1 PAC:37170661 Phaseolus vulgaris 309  
Phvul.003G041100.1.p V7C997 PAC:37148384 Phaseolus vulgaris 93  
Potri.001G126800.1.p A0A2K2BWQ2 PAC:37277017 Populus trichocarpa 500  
Podel.01G135700.1.p PAC:37308571 Populus deltoides WV94 610  
Oeu002302.1 PAC:37711720 Olea europaea 209  
Oeu051605.1 PAC:37729210 Olea europaea 86  
Gohir.A11G232200.1.p PAC:38085018 Gossypium hirsutum 195  
Gohir.A13G118000.1.p PAC:38155224 Gossypium hirsutum 124  
Isati.0660s0005.1.p PAC:39322370 Isatis tinctoria 209  
Luann.0115s0019.1.p PAC:39377477 Lunaria annua 145  
Thint.V0795400.1.p PAC:40916137 Thinopyrum intermedium 412  
MgTOL.D2207.1.p PAC:40968531 Mimulus guttatus TOL 104  
MgTOL.M1670.2.p PAC:40994733 Mimulus guttatus TOL 891  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10404215