Protein Domain : IPR006588

Type:  Domain Name:  Peptide N glycanase, PAW domain
Description:  The PAW domain (present in PNGases and other worm proteins) is found as a single copy at the C terminus of metazoan peptide:N-glycanase (PNGase)and in multiple copies in hypothetical Caenorhabditis elegansproteins peptide:N-glycanases (PNGases) []. The C-terminal PAW domain of PNGase binds to the mannose moieties of N-linked oligosaccharide chains [].The PAW domain is a slightly elongated molecule and displays a beta-sandwich architecture, which is composed of two layers, containing nine and eightantiparallel beta-strands, respectively, and three additional short helices [].Some proteins known to contain a PAW domain are listed below:Animal peptide:N-glycanase (PNGase) , catalyses the deglycosylation of several misfolded N-linked glycoproteins by cleaving thebulky glycan chain before the proteins are degraded by the proteasome. Caenorhabditis elegansputative uncharacterised protein C17B7.5. Short Name:  Peptide_N_glycanase_PAW_dom

0 Child Features

0 Contains

3 Cross Referencess

Identifier
PF04721
PS51398
SM00613

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0006516 IPR006588
GO:0005737 IPR006588

2 Ontology Annotations

GO Term Gene Name
GO:0006516 IPR006588
GO:0005737 IPR006588

1 Parent Features

DB identifier Type Name
IPR008979 Domain Galactose-binding domain-like

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11779830
            17088551