Type: | Family | Name: | NAD pyrophosphatase/5-nucleotidase NadN |
Description: | This family describes NadN of Haemophilus influenzaeand a small number of close homologues in pathogenic, Gram-negative bacteria. NadN is a periplasmic enzyme that cleaves NAD (nicotinamide adenine dinucleotide) to NMN (nicotinamide mononucleotide) and AMP. The NMN must be converted by a 5-nucleotidase to nicotinamide riboside for import. NadN belongs a large family of 5-nucleotidases and has NMN 5-nucleotidase activity for NMN, AMP, etc. | Short Name: | NadN |