Protein Domain : IPR028483

Type:  Family Name:  Sodium/hydrogen exchanger 10
Description:  This family of sodium/hydrogen exchangers is sperm-specific and is involved in intracellular pH regulation of spermatozoa, which is a critical regulator of both invertebrate and vertebrate sperm motility. Sodium/hydrogen exchanger 10 is involved in sperm cell hyperactivation, a step needed for sperm motility which is essential late in the preparation of sperm for fertilisation []. It is also required for the expression and bicarbonate regulation of the soluble adenylyl cyclase (sAC) []. Short Name:  N/H_exchanger_10

0 Child Features

0 Contains

1 Cross References

Identifier
PTHR10110:SF87

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0030317 IPR028483

1 Ontology Annotations

GO Term Gene Name
GO:0030317 IPR028483

1 Parent Features

DB identifier Type Name
IPR018422 Family Cation/H+ exchanger, CPA1 family

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            14634667
            17517652