Type: | Family | Name: | Sodium/hydrogen exchanger 10 |
Description: | This family of sodium/hydrogen exchangers is sperm-specific and is involved in intracellular pH regulation of spermatozoa, which is a critical regulator of both invertebrate and vertebrate sperm motility. Sodium/hydrogen exchanger 10 is involved in sperm cell hyperactivation, a step needed for sperm motility which is essential late in the preparation of sperm for fertilisation []. It is also required for the expression and bicarbonate regulation of the soluble adenylyl cyclase (sAC) []. | Short Name: | N/H_exchanger_10 |