| Type: | Family | Name: | Allergen Fel d 1, chain 2 |
| Description: | Allergies are hypersensitivity reactions of the immune system to specific substances called allergens (such as pollen, stings, drugs, or food) that, in most people, result in no symptoms. A nomenclature system has been established for antigens (allergens) that cause IgE-mediated atopic allergies in humans. The nomenclature system uses the first three letters of the genus, followed by the first letter of the species name, followed by a number (additional letters can be added to the name as required to discriminate between similar designations).Fel d 1 is allergen 1 from Felis silvestris catus(Cat), which is an important agent in human allergic reactions []. The protein is expressed in saliva and sebaceous glands. The complete primary structure of Fel d 1 has been determined []. The allergen is tetrameric glycoprotein consisting of two disulphide-linked heterodimers of chains 1 and 2, which have been shown to be encoded by different genes. Fel d 1 chains 1 and 2 share structural similarity with uteroglobin, a secretoglobin superfamily member; chain 2 is a glycoprotein with N-linked oligosaccharides.This entry represents Fel d 1 chain 2. | Short Name: | Allergen_Fel_d_1_chain2 |
