Protein Domain : IPR019909

Type:  Family Name:  Haem uptake protein IsdC
Description:  Isd proteins are iron-regulated surface proteins found in Bacillus, Staphylococcus and Listeria species and are responsible for haem scavenging from hemoproteins []. The IsdB protein is only observed in Staphylococcus and consists of an N-terminal hydrophobic signal sequence, a pair of tandem NEAT (NEAr Transporter, ) domains which confers the ability to bind haem [] and a C-terminal sortase processing signal which targets the protein to the cell wall. IsdB is believed to make a direct contact with methaemoglobin facilitating transfer of haem to IsdB []. The haem is then transferred to other cell wall-bound NEAT domain proteins such as IsdA and IsdC. Short Name:  Haem_uptake_protein_IsdC

0 Child Features

3 Contains

DB identifier Type Name
IPR006635 Domain NEAT domain
IPR017502 Domain Sortase B cell surface sorting signal
IPR017505 Domain Sortase B signal domain, NPQTN class

1 Cross References

Identifier
TIGR03656

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0030492 IPR019909
GO:0015886 IPR019909
GO:0009274 IPR019909

3 Ontology Annotations

GO Term Gene Name
GO:0030492 IPR019909
GO:0015886 IPR019909
GO:0009274 IPR019909

0 Parent Features

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            17229211
            18676371
            18467329