Protein Domain : IPR028271

Type:  Family Name:  RNMT-activating mini protein
Description:  This entry represents RNMT-activating mini protein (RAM), which is an essential component of the gene expression machinery required for mRNA cap methylation. RAM consists of an N-terminal RNMT-activating domain and a C-terminal RNA-binding domain [].In eukaryotes, the 7-methylguanosine cap added to the 5' end of mRNA is required for efficient gene expression. In mammals, methylation of the guanosine cap requires RNMT (RNA guanine-7 methyltransferase) []. The interaction between RNMT and RAM enhances the mRNA binding capacity and cap methyltransferase activity []. Short Name:  RAM

0 Child Features

0 Contains

1 Cross References

Identifier
PF15320

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0003723 IPR028271
GO:0032259 IPR028271
GO:0005845 IPR028271

3 Ontology Annotations

GO Term Gene Name
GO:0003723 IPR028271
GO:0032259 IPR028271
GO:0005845 IPR028271

0 Parent Features

0 Proteins

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            22099306