3 Ontology Annotations
GO Term | Gene Name |
---|---|
GO:0003723 | IPR028271 |
GO:0032259 | IPR028271 |
GO:0005845 | IPR028271 |
Type: | Family | Name: | RNMT-activating mini protein |
Description: | This entry represents RNMT-activating mini protein (RAM), which is an essential component of the gene expression machinery required for mRNA cap methylation. RAM consists of an N-terminal RNMT-activating domain and a C-terminal RNA-binding domain [].In eukaryotes, the 7-methylguanosine cap added to the 5' end of mRNA is required for efficient gene expression. In mammals, methylation of the guanosine cap requires RNMT (RNA guanine-7 methyltransferase) []. The interaction between RNMT and RAM enhances the mRNA binding capacity and cap methyltransferase activity []. | Short Name: | RAM |
GO Term | Gene Name |
---|---|
GO:0003723 | IPR028271 |
GO:0032259 | IPR028271 |
GO:0005845 | IPR028271 |