Protein Domain : IPR028312

Type:  Family Name:  Transcription factor E2F4
Description:  E2F4 is a member of the E2F family of transcription factors. E2F4 binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication []. In growth arrested cells, transcriptional activity by E2Fs is repressed by retinoblastoma (RB) proteins. E2F-4 can bind to RB and related proteins p130 to p107 []. Short Name:  E2F4
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0 Child Features

0 Contains

1 Cross References

Identifier
PTHR12081:SF42

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0003700 IPR028312
GO:0000278 IPR028312
GO:0006355 IPR028312

3 Ontology Annotations

GO Term Gene Name
GO:0003700 IPR028312
GO:0000278 IPR028312
GO:0006355 IPR028312

1 Parent Features

DB identifier Type Name
IPR015633 Family E2F Family

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9364211
            8657117