Protein Domain : IPR022881

Type:  Family Name:  Ribosomal RNA large subunit methyltransferase, Cfr
Description:  This entry represents the Cfr subfamily of RlmN methyltransferases.Ribosomal RNA large subunit methyltransferase Cfr specifically methylates position 8 of adenine 2503 in 23S rRNA. It can also methylate position 2 of A2503 after the primary methylation is complete, to form 2,8-dimethyladenosine. Cfr confers antibiotic resistance in bacteria. The antibiotic resistance is provided by methylation at the 8 position and is independent of methylation at the 2 position of A2503 [, ]. Short Name:  rRNA_lsu_MeTfrase_Cfr
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0 Child Features

0 Contains

2 Cross Referencess

Identifier
TIGR04432
MF_01873

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0070475 IPR022881

1 Ontology Annotations

GO Term Gene Name
GO:0070475 IPR022881

1 Parent Features

DB identifier Type Name
IPR004383 Family Ribosomal RNA large subunit methyltransferase RlmN/Cfr

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10952608
            19144912