3 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0003700 | IPR029836 |
| GO:0006357 | IPR029836 |
| GO:0005634 | IPR029836 |
1 Parent Features
| DB identifier | Type | Name |
|---|---|---|
| IPR016378 | Family | Transcription factor cyclic AMP-dependent, CRE-BP1-type |
| Type: | Family | Name: | cAMP-dependent transcription factor ATF-2 |
| Description: | Activating transcription factor or cAMP-dependent transcription factor ATF-2, also known as CRE-BP1, regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. ATF-2 needs to be phosphorylated by Jun N-terminal kinase (JNK), p38 (MAPK14), or extracellular-signal-regulated kinase 1 (ERK1) in order to be transcriptionally active. Activated ATF-2 then form dimers with proteins, such as members of the AP-1 family, and regulates gene transcription []. It has been implicated in several pathological conditions, including neurological diseases and cancer [, ]. | Short Name: | ATF-2 |
| GO Term | Gene Name |
|---|---|
| GO:0003700 | IPR029836 |
| GO:0006357 | IPR029836 |
| GO:0005634 | IPR029836 |
| DB identifier | Type | Name |
|---|---|---|
| IPR016378 | Family | Transcription factor cyclic AMP-dependent, CRE-BP1-type |
