Protein Domain : IPR022353

Type:  Conserved_site Name:  Insulin, conserved site
Description:  Insulin is involved in the regulation of normal glucose homeostasis, as well as other specific physiological functions []. It is synthesised as a prepropeptide from which an endoplasmic reticulum-targeting sequence is cleaved to yield proinsulin. Prosinsulin contains regions A and B separated by an intervening connecting region C. The connecting region is cleaved, liberating the active protein, which contains the A and B chains,held together by 2 disulphide bonds []. Short Name:  Insulin_CS

0 Child Features

0 Contains

1 Cross References

Identifier
PS00262

10 Found Ins

DB identifier Type Name
IPR016179 Domain Insulin-like
IPR016724 Family Insulin-related peptide
IPR022352 Family Insulin family
IPR004825 Family Insulin
IPR022350 Family Insulin-like growth factor
IPR022334 Family Insulin-like growth factor II
IPR022341 Family Insulin-like growth factor I
IPR017097 Family Bombyxin
IPR022421 Family Relaxin
IPR017100 Family Insulin-like peptide 6

0 GO Annotation

0 Ontology Annotations

0 Parent Features

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            503234
            6243748