Type: | Family | Name: | Ketol-acid reductoisomerase, fungi |
Description: | Ketol-acid reductoisomerases (KARI) catalyses two steps in the biosynthesis of branched-chain amino acids. The reaction involves an Mg2+ dependent alkyl migration followed by an NADPH-dependent reduction of the 2-keto group. There are two groups of KARI enzymes: class I is a short form found in fungi and most bacteria, and class II is a long form found in plants and certain bacteria (although their sequences differ) [, ]. However, there has also been a long form found in certain bacteria, but these differ from class II sequences found in plants.This group represents a ketol-acid reductoisomerase, fungal type. | Short Name: | KetolA_reductoisomerase_fun |