3 Ontology Annotations
GO Term | Gene Name |
---|---|
GO:0003677 | IPR028255 |
GO:0051382 | IPR028255 |
GO:0000776 | IPR028255 |
Type: | Family | Name: | Centromere protein T |
Description: | This entry represents the centromere protein T (CENP-T). CENP-T is a component of the CENPA-NAC (nucleosome-associated) complex, which plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation [, ]. CENP-T and CENP-W form a complex that is directly involved in establishment of centromere chromatin structure coordinately with CENP-A []. Histone-fold-containing CENP-T-W and CENP-S-X complexes can form a stable CENP-T-W-S-X heterotetramer. Structural analysis of the CENP-T-W-S-X complex suggests that it can form a unique nucleosome-like structure to generate contacts with DNA []. | Short Name: | CENP-T |
GO Term | Gene Name |
---|---|
GO:0003677 | IPR028255 |
GO:0051382 | IPR028255 |
GO:0000776 | IPR028255 |