Protein Domain : IPR028255

Type:  Family Name:  Centromere protein T
Description:  This entry represents the centromere protein T (CENP-T). CENP-T is a component of the CENPA-NAC (nucleosome-associated) complex, which plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation [, ]. CENP-T and CENP-W form a complex that is directly involved in establishment of centromere chromatin structure coordinately with CENP-A []. Histone-fold-containing CENP-T-W and CENP-S-X complexes can form a stable CENP-T-W-S-X heterotetramer. Structural analysis of the CENP-T-W-S-X complex suggests that it can form a unique nucleosome-like structure to generate contacts with DNA []. Short Name:  CENP-T

0 Child Features

0 Contains

1 Cross References

Identifier
PTHR14857

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0003677 IPR028255
GO:0051382 IPR028255
GO:0000776 IPR028255

3 Ontology Annotations

GO Term Gene Name
GO:0003677 IPR028255
GO:0051382 IPR028255
GO:0000776 IPR028255

0 Parent Features

0 Proteins

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            16622419
            16716197
            22304917
            19070575