Type: | Family | Name: | Cytoplasmic protein NCK |
Description: | Cytoplasmic protein NCK (NCK) is a family of non-enzymatic adaptor proteins composed of three SH3 (Src homology 3) domains and a C-terminal SH2 domain []. They associate with tyrosine-phosphorylated growth factor receptors or their cellular substrates [,]. They are implicated in organisation of actin cytoskeleton, cell movement or axon guidance []. There are two vertebrate NCK proteins, NCK1 and NCK2. | Short Name: | NCK |