Protein Domain : IPR017304

Type:  Family Name:  Cytoplasmic protein NCK
Description:  Cytoplasmic protein NCK (NCK) is a family of non-enzymatic adaptor proteins composed of three SH3 (Src homology 3) domains and a C-terminal SH2 domain []. They associate with tyrosine-phosphorylated growth factor receptors or their cellular substrates [,]. They are implicated in organisation of actin cytoskeleton, cell movement or axon guidance []. There are two vertebrate NCK proteins, NCK1 and NCK2. Short Name:  NCK

2 Child Features

DB identifier Type Name
IPR028524 Family Cytoplasmic protein NCK2
IPR028526 Family Cytoplasmic protein NCK1

2 Contains

DB identifier Type Name
IPR001452 Domain SH3 domain
IPR000980 Domain SH2 domain

1 Cross References

Identifier
PIRSF037874

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

0 Proteins

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9344857
            11240126
            21600986
            12034353