| Type: | Family | Name: | Mechanosensory protein 2 |
| Description: | Stomatin family members are oligomeric, they mostly localise to membrane domains, and in many cases have been shown to modulate ion channel activity []. Stomatin proteins have been identified in various organisms. There are nine stomatin-like proteins in C. elegans, mechanosensory protein 2 (MEC-2) is the best characterised [].MEC-2 positively regulates the activity of the mechanosensory transduction channels []. It is recruited to the putative mechanosensory complex in C. elegans touch receptor neurons through its stomatin-like domain []. MEC-2, like Podocin, binds cholesterol; in both cases cholesterol binding is required for the activity of the associated ion channels []. | Short Name: | MEC-2 |
