Type: | Family | Name: | Abl interactor 2 |
Description: | Abl interactor 2 (ABI2) belongs to the ABI family and participates in the formation of the Abi/WAVE complex, which regulates Arp2/3-mediated actin filament nucleation and actin network assembly [, , ]. Abl interactor 2 (Abi2) is a component of the WAVE1 complex. It localises to sites of actin polymerisation at the tips of lamellipodia and filopodia []. Its structure has been solved []. | Short Name: | Abi2 |