Protein Domain : IPR028492

Type:  Family Name:  Cartilage oligomeric matrix protein
Description:  Cartilage oligomeric matrix protein (COMP), or thrombospondin-5 (TSP-5), is a member of the thrombospondin gene family and is found mainly in the extracellular matrix often associated with cartilage tissue. It plays a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin [, , ]. COMP is involved in human limb development and in the pathogenesis of osteoarthritis []. Short Name:  Comp

0 Child Features

0 Contains

1 Cross References

Identifier
PTHR10199:SF81

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0005201 IPR028492
GO:0030198 IPR028492
GO:0005578 IPR028492

3 Ontology Annotations

GO Term Gene Name
GO:0005201 IPR028492
GO:0030198 IPR028492
GO:0005578 IPR028492

0 Parent Features

0 Proteins

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12225811
            19276170
            16051604
            16542502