Protein Domain : IPR017118

Type:  Family Name:  Peptidase S1A, matriptase-2
Description:  This entry contains serine peptidases belonging to MEROPS petidase family S1A (clan PA(S)), members are annotated as matriptase-2. Matriptase-2 is a type II transmembrane serine peptidase that plays a crucial role in body iron homeostasis by down-regulating hepcidin expression, which results in increased iron levels [, ]. Short Name:  Pept_S1A_matriptase-2
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0 Child Features

4 Contains

DB identifier Type Name
IPR002172 Repeat Low-density lipoprotein (LDL) receptor class A repeat
IPR000859 Domain CUB domain
IPR000082 Domain SEA domain
IPR018114 Active_site Peptidase S1, trypsin family, active site

1 Cross References

Identifier
PIRSF037135

0 Found In

0 GO Annotation

0 Ontology Annotations

1 Parent Features

DB identifier Type Name
IPR001314 Family Peptidase S1A, chymotrypsin-type

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            18451267
            20684597