Protein Domain : IPR017051

Type:  Family Name:  Peptidase S1A, matripase
Description:  This group represents matriptase, which is a type II transmembrane serine peptidase belonging to MEROPS peptidase family S1A (clan PA(S)). It is involved in a number of cellular processed that include: regulation of epithelial barrier formation and permeability in the intestine []; proteolytic cleavage of human acid-sensing ion channel 1 [] and the regulation of the matriptase-prostasin cell surface proteolytic cascade by hepatocyte growth factor activator inhibitor-1 during epidermal differentiation []. Short Name:  Peptidase_S1A_matripase
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0 Child Features

4 Contains

DB identifier Type Name
IPR002172 Repeat Low-density lipoprotein (LDL) receptor class A repeat
IPR000859 Domain CUB domain
IPR000082 Domain SEA domain
IPR018114 Active_site Peptidase S1, trypsin family, active site

1 Cross References

Identifier
PIRSF036370

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0004252 IPR017051
GO:0006508 IPR017051
GO:0016020 IPR017051

3 Ontology Annotations

GO Term Gene Name
GO:0004252 IPR017051
GO:0006508 IPR017051
GO:0016020 IPR017051

0 Parent Features

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            20142489
            20601429
            20696767