Protein Domain : IPR028650

Type:  Family Name:  Sorting nexin Lst-4
Description:  This entry represents the sorting nexin lst-4 (lateral signaling target). It belongs to the SNX9-family, which contains a SH3 domain, a PX (phox homology) domain and a BAR domain. In Caenorhabditis elegans, it is involved in the signaling of vulval development by acting as a negative regulator of epidermal growth factor receptor (EGFR) signalling []. Like its closest mammalian orthologue, SNX33, lst-4 also functions in the regulation of phagosome maturation during engulfment of apoptotic cells []. Short Name:  Lst-4
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0 Child Features

0 Contains

1 Cross References

Identifier
PTHR10555:SF11

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0005547 IPR028650
GO:0006886 IPR028650
GO:0090389 IPR028650
GO:0045335 IPR028650

4 Ontology Annotations

GO Term Gene Name
GO:0005547 IPR028650
GO:0006886 IPR028650
GO:0090389 IPR028650
GO:0045335 IPR028650

1 Parent Features

DB identifier Type Name
IPR014536 Family Sorting nexin 9 subfamily

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            14752159
            21494661