3 Ontology Annotations
GO Term | Gene Name |
---|---|
GO:0016491 | IPR005884 |
GO:0009061 | IPR005884 |
GO:0055114 | IPR005884 |
1 Parent Features
DB identifier | Type | Name |
---|---|---|
IPR014006 | Family | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit |
Type: | Family | Name: | Fumarate reductase, flavoprotein subunit |
Description: | In bacteria two distinct, membrane-bound, enzyme complexes are responsible for the interconversion of fumarate and succinate (): fumaratereductase (Frd) is used in anaerobic growth, and succinate dehydrogenase (Sdh) is used in aerobic growth. Both complexes consist of two main components: amembrane-extrinsic component composed of a FAD-binding flavoprotein and an iron-sulphur protein; and an hydrophobic component composed of a membraneanchor protein and/or a cytochrome B.In eukaryotes mitochondrial succinate dehydrogenase (ubiquinone) () is an enzyme composed of two subunits: a FAD flavoprotein and and iron-sulphurprotein.The flavoprotein subunit is a protein of about 60 to 70 Kd to which FAD is covalently bound to a histidine residue which is located in the N-terminalsection of the protein []. The sequence around that histidine is well conserved in Frd and Sdh from various bacterial and eukaryotic species [].The terms succinate dehydrogenase and fumarate reductase may be used interchangeably in certain systems. However, a number of species have distinct complexes, with the fumarate reductase active under anaerobic conditions. This model represents the fumarate reductase flavoprotein subunit from several such species in which a distinct succinate dehydrogenase is also found. | Short Name: | Fum_red_fp |
GO Term | Gene Name |
---|---|
GO:0016491 | IPR005884 |
GO:0009061 | IPR005884 |
GO:0055114 | IPR005884 |
DB identifier | Type | Name |
---|---|---|
IPR014006 | Family | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit |