| Type: | Family | Name: | Osteocalcin/matrix Gla protein |
| Description: | Bone gamma-carboxyglutamic acid protein (BGP), also known as Osteocalcin, and matrix gamma- carboxyglutamic acid protein (MGP) are the only vitamin K-dependent proteins that have been isolated from bone. MGP is a small protein found in bone, dentin and cartilage. It contains five gamma-carboxyglutamic acid (Gla) residues (formed by post-translational modification of glutamic acid by vitamin K-dependent carboxylase) and a single disulphide bond. BGP is a 49 residue protein found in bone. It contains three Gla residues and a single disulphide bond. There is little similarity between these vitamin K-dependent bone proteins and the blood coagulation proteins, though they are believed to have diverged from a common ancestor []. | Short Name: | Osteocalcin/MGP |
