Protein Domain : IPR014359

Type:  Family Name:  Ketol-acid reductoisomerase, bacteria
Description:  Ketol-acid reductoisomerases (KARI) catalyses two steps in the biosynthesis of branched-chain amino acids. The reaction involves an Mg2+ dependent alkyl migration followed by an NADPH-dependent reduction of the 2-keto group. There are two groups of KARI enzymes: class I is a short form found in fungi and most bacteria, and class II is a long form found in plants and certain bacteria (although their sequences differ) [, ]. However, there has also been a long form found in certain bacteria, but these differ from class II sequences found in plants.This entry represents bacterial type KARI. Short Name:  KetolA_reductoisomerase_bac
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0 Child Features

3 Contains

DB identifier Type Name
IPR000506 Domain Acetohydroxy acid isomeroreductase C-terminal
IPR008927 Domain 6-phosphogluconate dehydrogenase C-terminal domain-like
IPR013116 Domain Acetohydroxy acid isomeroreductase, NADPH-binding domain

1 Cross References

Identifier
PIRSF000116

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0004455 IPR014359
GO:0050661 IPR014359
GO:0009082 IPR014359
GO:0055114 IPR014359

4 Ontology Annotations

GO Term Gene Name
GO:0004455 IPR014359
GO:0050661 IPR014359
GO:0009082 IPR014359
GO:0055114 IPR014359

1 Parent Features

DB identifier Type Name
IPR013023 Family Ketol-acid reductoisomerase

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            16322583
            15272168