1 Contains
DB identifier | Type | Name |
---|---|---|
IPR004843 | Domain | Calcineurin-like phosphoesterase domain, apaH type |
3 Ontology Annotations
GO Term | Gene Name |
---|---|
GO:0016462 | IPR010138 |
GO:0009245 | IPR010138 |
GO:0005737 | IPR010138 |
Type: | Family | Name: | UDP-2,3-diacylglucosamine hydrolase |
Description: | This entry represents LpxH, or UDP-2,3-diacylglucosamine hydrolase (or diphosphatase), which is an essential enzyme in Escherichia colithat catalyses the fourth step in lipid A biosynthesis. This reaction involves pyrophosphate bond hydrolysis of the precursor UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate and UMP []. Several Gram-negative bacteria have homologues of LpxH and/or LpxH2, while others have only distant orthologues of LpxH or LpxH2, or lack these enzymes altogether []. | Short Name: | UDP-diacylglucosamine_Hdrlase |
DB identifier | Type | Name |
---|---|---|
IPR004843 | Domain | Calcineurin-like phosphoesterase domain, apaH type |
GO Term | Gene Name |
---|---|
GO:0016462 | IPR010138 |
GO:0009245 | IPR010138 |
GO:0005737 | IPR010138 |