Protein Domain : IPR028822

Type:  Family Name:  Nuclear receptor coactivator 2
Description:  Nuclear receptor coactivator 2 (NCOA2, also known as Tif2) belongs to the SRC/p160 nuclear receptor coactivator family, which contains proteins that are ligand-dependent transcription factors []. These receptors can function as molecular switches [].NCOA2 is a transcriptional coactivator for steroid receptors and nuclear receptors. It functions as a coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1) []. Together with NCOA1, it is required to control energy balance between white and brown adipose tissues []. Short Name:  NCOA2

0 Child Features

0 Contains

1 Cross References

Identifier
PTHR10684:SF2

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0030374 IPR028822

1 Ontology Annotations

GO Term Gene Name
GO:0030374 IPR028822

1 Parent Features

DB identifier Type Name
IPR017426 Family Nuclear receptor coactivator

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10713439
            12507421
            9430642