Protein Domain : IPR030195

Type:  Family Name:  Equilibrative nucleoside transporter 1
Description:  Human Equilibrative, Nitrobenzylthioinosine (NBMPR)-sensitive Nucleoside Transporter ENT1 was the first identified member of the ENT family. ENT1 (also known as solute carrier family 29 member 1, SLC29A1) mediates both influx and efflux of nucleosides across the membrane, including adenosine and many anti-cancer nucleoside drugs [, ]. ENT1 has a predicted topology of 11 transmembrane domains (TMDs) and a large hydrophilic loop in the region between TMD5 and TMD7 []. ENT1 -as ENT2- is localised in plasma membranes and is broadly expressed in tissues [, ]. Short Name:  ENT1

0 Child Features

0 Contains

1 Cross References

Identifier
PTHR10332:SF9

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0005337 IPR030195
GO:0015858 IPR030195
GO:0005887 IPR030195

3 Ontology Annotations

GO Term Gene Name
GO:0005337 IPR030195
GO:0015858 IPR030195
GO:0005887 IPR030195

1 Parent Features

DB identifier Type Name
IPR002259 Family Equilibrative nucleoside transporter

0 Proteins

5 Publications

First Author Title Year Journal Volume Pages PubMed ID
            23506887
            11584005
            12838422
            8986748
            11085929