Protein Domain : IPR030197

Type:  Family Name:  Equilibrative nucleoside transporter 2
Description:  Equilibrative nucleoside transporter 2 (ENT2), also known as solute carrier family 29 member 2 (SLC29A2), mediates transport of nucleosides and also efficiently transports nucleobases [] and hypoxanthine []. ENT2 has a predicted topology of 11 transmembrane domains (TMDs) and a large hydrophilic loop in the region between TMD5 and TMD7 []. ENT2 -as ENT1- is localised in plasma membranes and is broadly expressed in tissues [, ]. It is less sensitive than ENT1 to inhibition by nitrobenzylthioinosine (NBMPR), dipyridamole, dilazep and draflazine []. Short Name:  ENT2

0 Child Features

0 Contains

1 Cross References

Identifier
PTHR10332:SF8

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0005337 IPR030197
GO:0015858 IPR030197
GO:0005887 IPR030197

3 Ontology Annotations

GO Term Gene Name
GO:0005337 IPR030197
GO:0015858 IPR030197
GO:0005887 IPR030197

1 Parent Features

DB identifier Type Name
IPR002259 Family Equilibrative nucleoside transporter

0 Proteins

6 Publications

First Author Title Year Journal Volume Pages PubMed ID
            23506887
            11584005
            12838422
            9396714
            17473446
            18048066